Yes, you can migrate Microsoft 365 data from one tenant to another without using PowerShell. A third-party migration solution such as the Aryson Tenant to Tenant Migration Tool provides a GUI-based approach, which can be useful for administrators who prefer not to manage complex PowerShell scripts.

Aryson Tenant to Tenant Migration Tool supports migration of multiple Microsoft 365 workloads, including Exchange Online mailboxes, OneDrive, SharePoint, and Microsoft Teams. It can preserve mailbox folders and hierarchy while transferring OneDrive files and SharePoint content between the source and destination tenants.

The general process is:

1. Connect and authorize the source Microsoft 365 tenant.
2. Connect the destination tenant and provide the required permissions.
3. Map source users with their corresponding destination accounts.
4. Select the workloads to migrate—Mailbox, OneDrive, SharePoint, and Teams.
5. Apply selective or date-based filters if required.
6. Start the migration and monitor the progress through migration logs and reports.

The tool also provides features such as bulk user mapping, CSV import, batch processing, incremental migration, scheduling, and detailed reporting.

Therefore, if your objective is to perform a Microsoft 365 tenant-to-tenant migration without PowerShell, Aryson provides a centralized, GUI-based method for handling the major Microsoft 365 workloads from one tenant to another.